Linearized Vpr, Tat, E1A, p300 and CtBP1 molecules and their mutual conversation domains. Vpr interacts with GR and a number of other other NRs by way of its LxxLL motif located at amino acids 64 to 69. Binding sites of Vpr and p160-sort HAT coactivators overlap with one another on p300. Because Vpr includes a LxxLL motif just like p160 coactivator